Studies on Antiulcer Agents. IV. Antiulcer Effects of 2-Benzylthio-5,6,7,8-tetrahydro-4(3H)-quinazolinones and Related Compounds.

A Pharmacological Review on Natural Antiulcer Agents

INTRODUCTION: Ulcer is a common disorder of the gastrointestinal system, which causes much discomfort to patients, disrupting their daily routines and causes mental agony. Peptic ulcer is defined as a break off in the continuity of the mucosa of stomach or duodenum as a consequence of some medications like nonsteroidal anti-inflammatory drugs (NSAIDS), gastric acids and pepsin finally causes le...

Actions of antiulcer drugs.

Phenoxypropylamines: synthesis and antiulcer evaluation.

We have synthesized a number of phenoxypropylamines from N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}chloroacetamide (3). All the products have been characterized by elemental analysis, (1)H-NMR and MS. The biological activity effects of the title compounds were examined. From the biological activity results, we found that two of themshowed significant gastric acid antisecretory activity.

Gastric antisecretory and antiulcer effects of simvastatin in rats.

BACKGROUND AND AIM Recently, statins have appeared to have additional benefits beyond their lipid lowering effects, which has led to the interest in the use of this class of drugs outside the realm of cardiovascular disease. Simvastatin (SIM) is a commonly prescribed statin with anti-inflammatory and antioxidant properties. Excessive generation of oxygen-derived free radicals (ODFR) and proinfl...

Antiulcer Activity of Pipal Extract

An ethanol extract of Pipal has been studied for its ability to inhibit gastric acidity and to protect gastric mucosa against the injuries caused by pyloric ligation, acetyl salicylic acid and cytodestructing agents (80% ethanol, 06M Hcl and 0.2 M Hcl) in rats. The results of this study demonstrate that ethanol extract of papal has significant effects on various experimentally induced ulcers. I...